Bunionectomy as an Analgesic Model

Bunionectomy as an Analgesic Model In analgesic clinical trials, selecting the type of model to use can be challenging as each has their own pros and cons. As an analgesic model, Bunionectomy has excellent assay sensitivity.  In the paper linked below our Chief Scientific Officer, Dr. Neil Singla, discusses the clinical and experimental characteristics of four acute surgical … Read more

Measuring Respiratory Depression in Analgesic Studies

Measuring Respiratory Depression in Analgesic Studies Demonstrating that a novel analgesic provides pain relief but does not cause respiratory depression can be a significant challenge. Our Chief Scientific Officer, Dr. Neil Singla, has extensive expertise in clinical trials focusing on the evaluation of respiratory endpoints in analgesic studies. In a Phase 2b study in acute pain, … Read more

Reducing Placebo Response

In analgesic clinical trials, managing placebo response can make the difference between a successful study and a false negative outcome.