PHASE 1 & ANALGESIC PROOF-OF-CONCEPT
Multi-day confinement, pharmacokinetic and CSF collection
Lotus has the ability to house analgesic and surgical patients for up to 30 days in order to:
- Collect Pharmacokinetic and CSF Samples
- Control Study Confounders and Monitor Diary Data
- Ensure Medication Compliance
- Maintain Strictly Regimented Diet Plans
- Closely Observe for Safety
Located within a 675-Bed Multispecialty Community Hospital
Lotus operates a 40 bed phase 1 unit located within a community hospital, providing our clients with unprecedented access to medical subspecialists and technological resources. The emergency room is 100 yards away and the hospital code team will respond to our unit conferring an additional layer of safety to our subjects.
Contracts Independently And Utilizes Central IRB
Although Lotus is located inside a hospital it is an independent business unit which means that it can utilize a central IRB and execute contracts independently from the hospital. This results in rapid study starts that are not tied to the institutional bureaucracy typical of other hospital-based units.
Lotus Is Able To Perform Specialized Studies Requiring CSF Sampling (Both Intermittent And Continuous)
Understanding the distribution of pharmaceutical agents in the central compartment is important for many pharmaceutical products. At Lotus, we have performed several studies that have required continuous or intermittent CSF sampling. Continuous sampling is achieved by placing a multi‐orifice catheter in the patient’s intrathecal space. We have sampled continuously for up to 72 hours.