Liposomal drug-containing formulations are designed to provide slow release of drug over an extended period of time, thus extending duration while diminishing high plasma levels. In this study, we analyzed the pharmacokinetic properties of an investigational extended-release multivesicular liposomal formulation of bupivacaine (DepoFoam bupivacaine, DB, proposed proprietary name, EXPAREL™) after a single injection.
