Most studies simultaneously capture multiple endpoints that should logically flow in different directions, such as an increase in pain relief or a decrease in pain intensity. We customize remote data capture and monitoring for logical data queries for analgesic protocols.

Sponsors can use our proprietary system to compare analgesic scales and ensure that sites are correctly capturing critical study endpoints, as well as evaluating rescue medication usage and patient dropout rates. Utilizing our blinded data monitoring tools, sponsors can identify and fix a study’s methodical problems during (not after) the open enrollment period. 

Our specialty analgesic services include:

  • Video education training for subjects on such topics as:
    • How to rate pain using NPRS
    • What is placebo?
    • Use of rescue medication
    • Double stopwatch technique
    • And many more
  • Testing of subjects to evaluate their comprehension and need for further education regarding pain scales
  • Collection of intermittent and continuous Cerebrospinal Fluid (CSF) samples
  • Control for study cofounders
  • Assurance of strict compliance with investigational product and rescue medication
  • Ability to provide 24/7 critical care monitoring with an on-site anesthesiologist

Our Therapeutic Expertise

Therapeutic Expertise

In assisting with the advancement of pain therapies, Lotus Clinical Research seeks to invent and
operationalize research methods that improve study design and conduct for analgesic trials,
which support our mission to help alleviate the opioid crisis in society.