Delivering Complex, Specialized Clinical Trials

Since 2023, we have contributed to 32 FDA approvals, representing 27% of all drug approvals in the United States.*

Impact You Can Measure

Lotus Clinical Research is a global CRO specializing in neuroscience and metabolic clinical trials, including extensive experience in early-phase development. With our commitment to rigorous scientific results, we are an extension of your team providing expertise and insights to move your studies forward—from conception to market.

Where Strategic Science Meets Global Execution

Lotus Global Reach

Delivering scientifically rigorous trials wherever your program takes you.

Scientific Leadership Team

Hands-on navigation of the full development journey from startup to submission.

Neuroscience & Metabolic Excellence

We don’t run trials in every therapeutic area, just the ones woven into our DNA.

ERG’s Site Network

The fastest path to recruitment starts with launch-ready sites, expert PIs, and pre-qualified patients and normal healthy volunteers.

Global Reach for Global Trials

Lotus operates on a global scale, with a strong footprint across many countries. Our long-standing collaboration with partner CROs further extends our global reach, allowing us to support clinical trials in regions worldwide. We strategically select partners who complement our scientific expertise and share our values—while providing the leadership and oversight needed to ensure quality and efficiency throughout every engagement.

Global Reach

Turning Insight Into Impact: How Scientific Leadership Strengthens Your Study from Day One

Behind every successful trial at Lotus is a deeply engaged Scientific Leadership Team—a cross-functional group of experienced clinicians, scientists, and research experts. From the moment a protocol is reviewed, this team plays an active role in identifying risk, shaping study strategy, and guiding execution. Sponsors don’t just gain operational support—they gain a thought partner. With hands-on involvement from startup through closeout, we help ensure every trial is smarter, stronger, and better positioned for success.

Specialized Therapeutic Expertise Backed by Real-World Results

With experience conducting thousands of clinical trials spanning CNS and metabolic diseases, our team brings unmatched depth across two of the most complex and interconnected therapeutic areas.

Psychiatry

1800+ studies across all major mental health diseases

Pain

600+ studies in acute and chronic pain

Neurology

1600+ studies across all phases of development

Addiction

70+ studies to treat addiction and prevent relapse

Metabolic & Endocrinology

125+ studies in metabolic-related disease, including obesity

ERG’s Site Network: Streamlines and Drives Efficiency

Lotus and Evolution Research Group (ERG) operate under common ownership and work as a fully integrated research partnership. We deliver end-to-end support across all phases of clinical development by combining ERG’s extensive clinical site network and Lotus’ full-service CRO capabilities. Our collaboration is grounded in shared scientific leadership, operational excellence, and a deep focus on complex therapeutic areas. This collaboration streamlines timelines, enhances data quality, and enables faster, more efficient delivery of even the most complex trials.

*Statistics combine experience from Lotus Clinical Research, Evolution Research Group, and Summit Analytical.