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Data Imputation Techniques for Analgesic Clinical Trials

When it comes to subject dropouts, an ounce of prevention is worth a pound of cure. Lotus Clinical Research has created a subject and investigator education series that can reduce subject dropout rates.

In the FDA Draft Analgesic Guidance, the agency devoted extensive discussion to the appropriate statistical handling of missing data.  The following video on accepted imputation techniques for acute and chronic analgesic studies may be of interest to you: