When it comes to subject dropouts, an ounce of prevention is worth a pound of cure. Lotus Clinical Research has created a subject and investigator education series that can reduce subject dropout rates.
The prevailing soft tissue acute pain surgical models (hemorrhoidectomy, herniorrhaphy, hysterectomy, laparoscopic cholecystectomy, colon surgery) are slow to recruit and present financial and logistical challenges
Bunionectomy as an Analgesic Model In analgesic clinical trials, selecting the type of model to use can be challenging as each has their own pros and cons. As an analgesic model, Bunionectomy has excellent assay sensitivity. In the paper linked below our Chief Scientific Officer, Dr. Neil Singla, discusses the clinical and experimental characteristics of four acute surgical … Read more
Measuring Respiratory Depression in Analgesic Studies Demonstrating that a novel analgesic provides pain relief but does not cause respiratory depression can be a significant challenge. Our Chief Scientific Officer, Dr. Neil Singla, has extensive expertise in clinical trials focusing on the evaluation of respiratory endpoints in analgesic studies. In a Phase 2b study in acute pain, … Read more
3rd Molar Extraction as an Analgesic Model In analgesic clinical trials, selecting the type of model to use can be challenging as each has their own pros and cons. As an analgesic model, 3rd molar extraction has excellent assay sensitivity. Additionally, because of its low cost and rapid enrollment, it can be used to cost effectively dose … Read more